Facebook
Twitter
LinkedIn
Email
 |
Checking for direct PDF access through Ovid | |
Excerpt
Materials and Methods: A prospective, randomized, double-blind study comparing two agents for topical anaesthesia in cataract surgery is reported. One hundred and twenty consecutive cases undergoing clear corneal phacoemulsification were enrolled into two groups, receiving either topical 0.75% levobupivacaine (n = 60) or 2% lidocaine (n = 60). The main outcome measures of the study were intraoperative and postoperative pain, requirement for additional anaesthesia, comfort and cooperation of the patient, and corneal epithelial toxicity induced by topical drugs. Systolic and diastolic blood pressure, pulse rate and peripheral oxygen saturation were recorded preoperatively and during surgery.
Results and Discussions: Levobupivacaine 0.75% provided significantly better topical anaesthesia than lidocaine 2% during cataract surgery (p = 0.003) and at the follow-up (p = 0.007). There were no statistically differences between the two groups thirty minutes and five hours after surgery. Epithelial toxicity was similar in both groups. Satisfactory comfort of the patient and the surgeon assessment of patient cooperation were clinically better in the levobupivacaine groups.
Conclusion(s): Levobupivacaine 0.75% was more effective than lidocaine 2% for topical anaesthesia in clear corneal phacoemulsification, providing better operative conditions and less systemic toxicity.
