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Excerpt
Materials and Methods: In this study we evaluated the perioperative coagulation profile using both standard laboratory work and TEG in pediatric patients undergoing craniotomy for primary brain tumors. 40 Pediatric patients were enrolled in the study. All patients received standard anesthesia. Blood was analyzed for both standard laboratory work and TEG at three points for each patient: preoperatively, intraoperatively, and postoperatively. Post operatively patients were divided into two groups according to occurrence or not of postoperative haematomas.
GNH (non haematoma group) and GH (haematoma group). The standard blood work and TEG values for both groups were compared.
Results and Discussion: Perioperative standard blood work was within normal limits for all patients with no significant difference between both groups. In GNH TEG values were indicative of a hypercoagulable state which started intraoperative and continued into the 1st postoperative day. In GH TEG values were indicative of a hypocoagulable state which was evident in the preoperative TEG values and continued into the intraoperative as well as post operative period.
Conclusion: TEG may be useful in the perioperative assessment and monitoring of coagulation in pediatric neurosurgical patients and helps in identifying patients at increased risk of bleeding or thromboembolic events.
