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Excerpt
Materials and Methods: The prospective study included 50 pediatric patients with clinically suspected appendicitis aged 5 to 15 years, who underwent appendectomy. Children were randomized into two groups 25 patients each with non- perforated appendicitis (ANP) and with perforated appendicitis (AP). Body temperature -axilar, rectal; total count of white blood cell, WBC; percentage of neutrophils, Ne; C- reactive protein, CRP; and procalcitonin, PCT concentrations were followed before surgry as well as duration of fewer and postoperative hospital stay. Measurement of PCT concentration was carried out by immunoluminometric assay and CRP concentration by immunonephelometric assay.
Results and Discussion: There was no difference in demographic characteristics such as age, body mass, sex between patient groups. Higher axilar (38,02 +/− 0,7 vs 37,23 +/− 0,73 °C; p<0,001), rectal (38,67 +/− 0,75 vs 37,8 +/− 0,8 °C; p<0,001) body temperature and longer duration of fewer (5,2 +/− 3,78 vs 2,0 +/− 0,97 days; p,0,001) was recorded in AP group comparing to ANP. Duration of postoperative hospital stay was longer in AP group (7,22 +/− 1,57 vs 14,0 +/− 6,41 days; p<0,001). There was no difference between total count of white blood cell, WBC (18,31 +/− 7,77 vs 14,44 +/− 5,28 x103/ìL; p>0,05) and percentage of neutrophils (80,29 +/− 8,29 vs 76,65 +/− 11,18%; p>0,05) between groups, while CRP (85,36 +/− 44,89 vs 18,49 +/− 24,15 mg/L; p<0,001) and PCT (9,26 +/− 8,23 vs 0,13 +/− 0,12 ng/ml; p<0,001) concentrations were significantly higher in AP group.
Conclusion(s): Clinical and laboratory parameters such are axilar, rectal temperature, duration of fewer in days as well as CRP and PCT concentrations might be useful in differentiation of higher risk patients with perforated appendicitis, that require longer postoperative hospital stay.
