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HUNTER, S. K., J. DUCHATEAU, and R. M. ENOKA. Muscle fatigue and the mechanisms of task failure. Exerc. Sport Sci. Rev., Vol. 32, No. 2, pp. 44–49, 2004. An alternative approach in the study of muscle fatigue is to address the question, “What causes task failure during a fatiguing contraction?” This approach is described by considering how variation in the type of load supported and contraction intensity influence both the time to task failure and the centrally mediated adjustments in reflex activity and motor unit behavior.