1University of California, San Francisco, CA; 2San Francisco Veterans Affairs Medical Center, San Francisco, CA; and 3Division of Research, Kaiser Permanente, Oakland, CA, United States
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Abstract
Dementia is a common and debilitating disease that will increase dramatically for the next 50 years unless a prevention or treatment is identified. This review summarizes the evidence that physical activity is associated with a reduced risk of dementia in older adults and recommends that prevention trials be performed to determine whether this association is causal.