Preparation of Xenon-133 in a Lipid Emulsion for Tissue Perfusion Studies

Abstract

A simple, inexpensive technique for concentrating xenon-133 in a medium suitable for intravenous use is reported. The method uses a 20% lipid emulsion, standard syringes, an oscillating motor, and xenon-133, which is available commercially. Typically, 43% of the xenon-133 combines with the lipid emulsion and remains stable for more than 24 hours in vitro.