Simple Bone Cysts: Studies of Cyst Fluid in Six Cases with a Theory of Pathogenesis

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Cyst fluid of six simple cysts of bone was aspirated and determinations of electrolytes and protein content made. In four of the cysts the fluid resembled plasma. In two others it resembled blood. A theory of etiology of simple cysts is suggested in which the principal etiological factor is blockage of the drainage of interstitial fluid in a rapidly growing and rapidly remodeling area of cancellous bone.

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