Pathological fractures in patients who have amyloidosis associated with dialysis. A report of five cases.


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Abstract

We are reporting the cases of five patients in whom a pathological fracture of the femoral neck developed secondary to massive deposition of amyloid while they were receiving maintenance hemodialysis. The immunohistochemical studies demonstrated the presence of beta-2-microglobulin as the major constituent protein of the amyloid deposits.

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