DOI: 10.1097/01.yic.0000423249.51629.87

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Issn Print: 0268-1315

Publication Date: 2012/12/01


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Sub-threshold bipolar and reaction to stress and grief

L Dell’Osso

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Excerpt

Introduction: The aim of the present study was to explore the relationship between sub-threshold mood symptoms and suicidality in patients with complicated grief (CG).
Methods: Fifty patients with CG were included in the study and evaluated by the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition Axis-I disorders, the Inventory of Complicated Grief, and the Mood Spectrum Self Report (MOODS-SR) lifetime version, to evaluate the sub-threshold mood symptoms.
Results: Twenty-eight patients (56%) reported lifetime suicidal ideation and 11 patients (22%) reported suicide attempts. Sub-threshold depressive and rhythmicity/ vegetative functions items of the MOODS-SR were significantly associated with increased suicidal ideation and attempts, while sub-threshold manic items were associated with suicidal ideation only. Relationships were confirmed after controlling for Axis-I disorders comorbidity.
Conclusion: The results of the present study suggest the usefulness of exploring lifetime sub-threshold mood symptoms in CG patients, in order to promptly identify those who may be more prone to suicidality.
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