PMID: 10896077
Issn Print: 0277-2116
Publication Date: 2000/07/01
Perianal Crohn's Disease in Infancy
Dinesh Pashankar; Richard A Schreiber; David M Israel
Excerpt
Crohn's disease, primarily a disease of older children and young adults, is rare in the first year of life. At this young age, Crohn's disease usually manifests with severe diarrhea and failure to thrive or with small bowel obstruction requiring surgical intervention. The clinical course is often fulminant with rates of high morbidity and mortality (1–6). Although perianal disease has been described in this group (4,5), systemic symptoms related to small bowel and colonic inflammation usually dominate the clinical picture. The diagnosis of Crohn's disease is difficult in infants who have perianal disease with no systemic symptoms. We report three infants who had recurrent perineal lesion as the sole manifestation of Crohn's disease.
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