PMID: 12960656
Issn Print: 0277-2116
Publication Date: 2003/09/01
Acute Pulmonary Edema After Intravenous Propofol Sedation for Endoscopy in a Child
Ying-Tai Tai; Chih-Ta Yao; Yao-Jong Yang
Excerpt
Propofol (2, 6-diisopropylphenol) sedation for endoscopic examinations and various minor outpatient procedures is considered safe and effective in children (1–3). Propofol is an ultrashort-acting intravenous hypnotic, formulated in a lipid emulsion. The pediatric sedative combinations of midazolam and propofol have been widely used for reducing the propofol dosage (1). Side effects of propofol are uncommon, and most are mild, transient, and without permanent sequelae. In one retrospective review, the common adverse events encountered in children were hypotension (50%), respiratory depression (6%), and myoclonus (3.6%) (3). Acute onset pulmonary edema after the administration of propofol has rarely been reported. In Asia, only two adult cases have been reported (4,5). The authors report a pediatric case in which the administration of propofol was associated with acute pulmonary edema before gastrointestinal endoscopic examination.
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