Caveats for the Use of Operational Electronic Health Record Data in Comparative Effectiveness Research

William Hersh;Mark Weiner;Peter Embi;Judith Logan;Philip Payne;Elmer Bernstam;Harold Lehmann;George Hripcsak;Timothy Hartzog;James Cimino;Joel Saltz;

doi:10.1097/MLR.0b013e31829b1dbd

Medical Care. 51():S30–S37, AUGUST 2013

DOI: 10.1097/MLR.0b013e31829b1dbd

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PMID: 23774517

Issn Print: 0025-7079

Publication Date: August 2013

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William Hersh;Mark Weiner;Peter Embi;Judith Logan;Philip Payne;Elmer Bernstam;Harold Lehmann;George Hripcsak;Timothy Hartzog;James Cimino;Joel Saltz;

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Abstract

The growing amount of data in operational electronic health record systems provides unprecedented opportunity for its reuse for many tasks, including comparative effectiveness research. However, there are many caveats to the use of such data. Electronic health record data from clinical settings may be inaccurate, incomplete, transformed in ways that undermine their meaning, unrecoverable for research, of unknown provenance, of insufficient granularity, and incompatible with research protocols. However, the quantity and real-world nature of these data provide impetus for their use, and we develop a list of caveats to inform would-be users of such data as well as provide an informatics roadmap that aims to insure this opportunity to augment comparative effectiveness research can be best leveraged.


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Caveats for the Use of Operational Electronic Health Record Data in Comparative Effectiveness Research

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