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PASCOE, D. D., D. L. COSTILL, W. J. FINK, R. A. ROBERGS, and J. J. ZACHWIEJA. Glycogen resynthesis in skeletal muscle following resistive exercise. Med. Sci. Sports Exerc., Vol. 25, No. 3, pp. 349–354, 1993. The purpose of this investigation was to determine the influence of post-exercise carbohydrate (CHO) intake on the rate of muscle glycogen resynthesis after high intensity weight resistance exercise in subjects not currently weight training. In a cross-over design, eight male subjects performed sets (mean = 8.8) of six single leg knee extensions at 70% of one repetition max until 50% of full knee extension was no longer possible. Total force application was equated between trials using a strain gauge interfaced to a computer. The subjects exercised in the fasted state. Post-exercise feedings were administered at 0 and 1 h consisting of either a 23% CHO solution (1.5 g-kg-1) or an equal volume of water (H2O). Total force production, preexercise muscle glycogen content, and degree of depletion (-40.6 and −44.3 mmol-kg-1 wet weight) were not significantly different between H2O and CHO trials. As anticipated during the initial 2-h recovery, the CHO trial had a significantly greater rate of muscle glycogen resynthesis as compared with the H2O trial. The muscle glycogen content was restored to91%and75%of preexercise levels when water and CHO were provided after 6 h, respectively.