Issn Print: 0195-9131
Publication Date: 1997/05/01
CARDIOVASCULAR DYNAMICS AT THE ONSET OF EXERCISE 208
R. L. Hughson; M. J. Joyner; L. Walløe; M. D. Delp; M. H. Laughlin; J. K. Shoemaker
Excerpt
The mechanisms responsible for the rapid hyperemia at the onset of exercise continue to be important topics for research. In this symposium, we will examine the increase in cardiac output and its distribution to vascular beds of working and non-working regions of the body. To the extent possible, the research presented will focus on experimental results from studies of humans. Great advances in non-invasive technologies and the ability to achieve specific local interactions with the control mechanisms have allowed us to explore these issues in finer detail. Animal research will continue to supplement our investigations and will provide a basis for the future studies of exercise hyperemia. After introductory remarks, Dr. Walløe will describe the development of Doppler ultrasound methods that have been used to provide information on the detailed time course of beat-by-beat changes in cardiac output and skeletal muscle blood flow. The topic of vasodilation will be explored by Dr. Delp in an overview of the current understanding of neural, vascular and metabolic control mechanisms. Dr. Laughlin will explore exercise hyperemia by providing a critique of research methods used to study competing hypotheses. Dr. Shoemaker will provide details of experiments with human subjects that have examined the rapid hyperemia with dynamic muscle contractions. Finally, Dr. Joyner will synthesize the major unresolved issues and he will speculate on how we might obtain answers to these long standing important questions in exercise physiology.
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