Issn Print: 0195-9131
Publication Date: 1997/05/01
LOW FREQUENCY EXERCISE CONDITIONING IMPROVES FUNCTIONAL PERFORMANCE BUT NOT VO2peak IN END STAGE RENAL DISEASE 957
Excerpt
This study examined the effects of a 12 week programme of pre-conditioning on peak oxygen uptake (VO2peak), isometric leg strength and functional status of people with end stage renal disease (ESRD). Sixteen self-selected patients [12 men, 4 women (M±SD); 63.6±11, range 44-78 yrs; 73.6±9.6 kg] receiving maintenance dialysis were recruited to the study and assigned to either a pre-conditioning (PC) or control (CON) group. VO2peak (1.24±0.34 1.min; 16.85±3.0 ml.kg.min-1) measured online during a progressive incremental cycle ergometer protocol and isometric leg strength assessed at 90 degrees of knee flexion (93.3±40 N; 1.25±0.5 N kg) were determined prior to and following the pre-conditioning programme for PC group. A timed continuous walking/stairclimbing task (WALK) [comprising a 50 metre walk, climb of 1 regulation flight of stairs, descent, 50 metre walk; WALK and VO2peak ml.kg.min-1, r = -.81, p<0.005; WALK test-retest r = 0.98, p<0.001] and walking impairment questionnaire (WIQ) were completed by PC and CON groups before and after the intervention. The pre-conditioning programme consisted of 24 exercise sessions (2/week) incorporating 15 minutes of accumulated cycle ergometer exercise, at an exercise intensity corresponding to RPE13 derived from GXT, in combination with a leg/abdominal muscular endurance circuit. Following the pre-conditioning programme no significant differences were observed for either VO2peak or isometric leg strength. Repeated measures ANOVAs revealed significant group (PC.CON) by time (Pre, Post) interactions for the WALK task with improvements for the PC group alone in Total Walk Time of 146±38 s to 126±31 s(p<0.03). Stair Climb of 18.8±5.4 s to 14.8±4.2 s(p<0.001) and Stair Descent of 21.7±11 s to 17.8±7.8 s(p<0.05). These findings indicate that for people with ESRD functional performance can be favourably altered by periods of exercise conditioning at dosages insufficient to increase VO2peak.