|| Checking for direct PDF access through Ovid
This experiment examined the influence of acute exercise on anxiety following caffeine-induced elevations in self-rated anxiety.Eleven physically active, moderately fit males aged 25.1 ± 3.8 yr completed four conditions in a within-subject, counterbalanced design involving 60 min of (1) cycling at 60% ˙VO2peak or (2) quiet rest following placebo consumption (800 mg of lactose), as well as (3) cycling at 60% ˙VO2peak and (4) quiet rest following 800 mg of caffeine. State anxiety and blood pressure were assessed 10 min before and 10 and 20 min after the conditions.A main effect for drug (caffeine vs placebo) determined by repeated measures ANOVA, (F(1,8) = 9.77; P = 0.01), indicated that state anxiety was elevated by caffeine. Drug effects were not obtained for blood pressure. Experimental hypotheses were tested by drug-by-condition(exercise vs quiet rest)-by-time (10 and 20 min postcondition) repeated measures ANOVA of change scores from the precondition baseline. A main effect for drug (F(1,8) = 5.81; P = 0.043) indicated that reductions in state anxiety were larger after caffeine ingestion. A condition-by-time effect (F(1,8) = 5.02; P = 0.055) indicated greater reductions in state anxiety 20 min after exercise compared with quiet rest. A condition effect for systolic blood pressure(F(1,10) = 4.56; P = 0.058) and condition-by-time interactions for diastolic (F(1,10) = 8.87; P = 0.014) and mean arterial blood pressures (F(1,10) = 8.46; P = 0.016) indicated reductions after exercise but not after quiet rest following both caffeine and placebo.We conclude that exercise can reduce anxiety elevated by a high dose of caffeine.