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Excerpt
The primary objective of this study was to determine if changes in fat free mass(STM) and fat mass (FM) due to weight loss were assessed similarly using DXA Fan Beam (FB)(QDR4500 Hologic, Inc.) and Pencil Beam (PB) (QDR2000) technology. 43 individuals enrolled in a weight loss program STM and FM measured at baseline and at follow-up. STM and FM was obtained by performing a whole body DXA using both the FB and PB. The mean weight loss was 5.9 ± 4.5 kg. FM assessed by the PB was higher at baseline and follow-up and STM (kg.) was lower as indicated in this table (**p<0.001; *p<0.04) FB PB Difference Correlation Baseline 52.1 ± 5.4 46.1 ± 5.3 −6.1 ± 1.9** 0.98** Follow-up 48.9 ± 6.1 43.5 ± 6.0 −5.4 ± 1.7** 0.97** Change −1.6 ± 2.0 −0.9 ± 2.2 −0.7 ± 1.4** 0.78* Using the model; STM = Scale Weight + Beam Indicator, the relationship between the FB and PB was deemed to be parallel at baseline (p<0001), follow-up(p<0001) and change, (p<0.04) across the range for weight (65.3-122.2 kg) and weight change(4.1 - 13.9 kg). This study demonstrated that the pencil beam consistently assesses lower levels of STM and higher levels of FM than the fan beam both cross-sectionally and with weight change. Additionally, the agreement between the two beams when ranked into tertiles had a kappa =0.536 (0.325,0.746 95%CI) for change in STM. Whether the FB or PB provides the correct assessment of STM and FM rem ms to be determined.
