Effects of Pseudoephedrine on Maximal Cycling Power and Submaximal Cycling Efficiency


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Abstract

HODGES, A. N. H., B. M. LYNN, J. E. BULA, M. G. DONALDSON, M. O. DAGENAIS, and D. C. MCKENZIE. Effects of Pseudoephedrine on Maximal Cycling Power and Submaximal Cycling Efficiency. Med. Sci. Sports Exerc., Vol. 35, No. 8, pp. 1316–1319, 2003.PurposeTo study the effects of a therapeutic dose of pseudoephedrine on anaerobic cycling power and aerobic cycling efficiency.MethodsEleven healthy moderately trained males (V̇O2peak 4.4 ± 0.8 L·min−1) participated in a double-blinded crossover design. Subjects underwent baseline (B) tests for anaerobic (Wingate test) and aerobic (V̇O2peak test) cycling power. Subjects ingested either 60 mg of pseudoephedrine hydrochloride (D) or a placebo (P) and, after 90 min of rest, a Wingate and a cycling efficiency test were performed. During the cycling efficiency test, heart rate (HR) and V̇O2 were averaged for the last 5 min of a 10-min cycle at 40% and 60% of the peak power achieved during the V̇O2peak test.ResultsThere were no significant differences in peak power (B = 860 ± 154, D = 926 ± 124, P = 908 ± 118 W), total work (B = 20 ± 3, D = 21 ± 3, P = 21 ± 3 kJ), or fatigue index (B = 39 ± 8, D = 45 ± 5, P = 43 ± 5%). There were no significant differences in HR at 40% power (D = 138 ± 10, P = 137 ± 10 beats·min−1) or 60% power (D = 161 ± 11, P = 160 ± 11 beats·min−1). There were no significant differences in cycling efficiency at 40% power (D = 18.8 ± 1.8, P = 18.5 ± 1.8%) or 60% power (D = 20.3 ± 2.0, P = 20.1 ± 2.1%).ConclusionA therapeutic dose of pseudoephedrine hydrochloride does not affect anaerobic cycling performance or aerobic cycling efficiency.

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