Issn Print: 0195-9131
Publication Date: 2005/05/01
Exercise Endurance Capacity Is Dependent On Hexokinase II Protein Content In C57Bl/6J Mice: 57 10:30 AM - 10:45 AM
Patrick T. Fueger; Jane Shearer; Tess M. Krueger; Kelly A. Posey; David H. Wasserman
Excerpt
Glucose phosphorylation is a key site for controlling muscle glucose uptake (MGU) during exercise since hexokinase II (HK) overexpression augments exercise-stimulated MGU and reductions in HK attenuate exercise-stimulated MGU. We hypothesized that modifying free glucose influx into the working muscle would spare glycogen and delay fatigue.
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