Cellular Response To Exercise Induced Oxidative Stress And The Effect Of Diet Composition In Trained Athletes: 2300 <i>board #89</i> 9:00am – 10:30am

Madlyn I. Frisard; Anthony E. Civitarese; Steven R. Smith; Eric Ravussin; D Enette Larson-meyer

Issn Print: 0195-9131

Publication Date: 2005/05/01

Cellular Response To Exercise Induced Oxidative Stress And The Effect Of Diet Composition In Trained Athletes: 2300 Board #89 9:00AM – 10:30AM

Madlyn I. Frisard; Anthony E. Civitarese; Steven R. Smith; Eric Ravussin; D Enette Larson-Meyer


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Excerpt

Intense exercise is known to increase free radical production resulting in increased oxidative damage. This results in the up regulation of genes that protect cells against adverse effects of oxidative stress and induces the expression of NADPH ubiquinone oxidoreductase (NQO1) and heme oxygenase-1 (HO1). It has recently been suggested that NQO1 can directly scavenge superoxide radicals. In addition, HO1 has been shown to increase following muscular contractions. However, there are few studies that have examined the effects of dietary fat on exercise-induced oxidative stress.


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