CHILDHOOD EMPYEMA: LIMITED POTENTIAL IMPACT OF 7-VALENT PNEUMOCOCCAL CONJUGATE VACCINE


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Abstract

During 2003–2004, locally presenting pleural empyema cases in children increased 3-fold. Antigen analysis of empyema fluid identified Streptococcus pneumoniae in 27 of 29 cases for whom samples were available and capsular polysaccharide type 1 in 18 of these. Use of a conjugate vaccine without serotype 1 antigen would have had limited impact on this morbidity in our region.

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