Cosmetic Treatment of Shagreen Patches in Selected Patients with Tuberous Sclerosis


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Abstract

SUMMARYPatients with mild forms of tuberous sclerosis may request cosmetic treatment of skin hamartomas. Treatment may consist of planing of an elevated shagreen patch with a Reese dermatome and/or laser treatment of facial angiofibromas. These precise patients, i.e., patients with a forme fruste of tuberous sclerosis, are more likely to have pulmonary involvement than patients with the usual complete disease form. A chest x-ray should be obtained in these patients to rule out pulmonary involvement. Half the patients with pulmonary involvement of tuberous sclerosis die an avoidable death from spontaneous pneumothoraces. Positive-pressure ventilation during anesthesia in these patients should be avoided or monitored closely.

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