DOI: 10.1097/01.prs.0000430007.16260.75
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Issn Print: 0032-1052
Publication Date: 2013/05/01
Abstract 65: VON FREY MEASUREMENTS DISCRIMINATE BETWEEN SITE SENSATION
Andrej Nedic; JD Moon; TA Kung; NB Langhals; PS Cederna; MG Urbanchek
Excerpt
Regenerative peripheral nerve interfaces (RPNI) are used to transduce motor nerve signals to and electrical sensory signals from a robotic arm. Quantification of sensory feedback is essential to assessment of closed loop neural continuity. Von Frey (VF) filament testing has traditionally been used clinically for this purpose but has not been validated in the rodent. Our purpose was to (a) determine the ideal, 8-filament range for VF sensation measurements in the ankle and thigh of the rat, (b) determine the reliability at both locations and (c) apply the test in experimental studies of Mixed Nerve (MN) and Sensory Nerve (SN) RPNIs.
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