Issn Print: 0885-3177
Publication Date: 2006/11/01
ANTIBIOTIC PROPHYLAXIS IN NECROTISING PANCREATITIS: RELATION OF METHODOLOGICAL QUALITY OF RANDOMISED CONTROLLED TRIALS TO OUTCOME
M.G. H. Besselink; A.C. de Vries; C.I. B. van de Kraats; E. Buskens; K.J. Van Erpecum; H.G. Gooszen
+ Author Information
Author Information: Gastrointestinal Research Unit, Departments of Gastroenterology and Surgery,
Excerpt
Infection of pancreatic necrosis is the most important cause of late mortality in necrotising pancreatitis (NP). The available evidence on the prevention of infection by systemic antibiotic prophylaxis is conflicting and the methodological quality of the published trials has been criticised. At present there is no international consensus on the indication for antibiotic prophylaxis in ANP.