Stress, Early Experience and Adjuvant-Induced Arthritis in the Rat

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Group-housing stress significantly increases the intensity of adjuvant-induced arthritis in the male Fischer rat and can accelerate the time of maximal disease and rate of recovery. Handling in infancy does not alter disease in the adult animal. There are no significant differences in serum proteins, plasma adrenal corticosteroids or fibrinogen between stressed and nonstressed animals.

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