ASSESSMENT OF VISION-RELATED QUALITY OF LIFE IN PATIENTS WITH CENTRAL RETINAL ARTERY OCCLUSION

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Abstract

Background:

Central retinal artery occlusion (CRAO) is a major cause for severe visual impairment. Its effect on vision-related quality of life has not yet been determined. The purpose of the present study was thus to assess vision-related quality of life in patients with CRAO using the 39-item National Eye Institute Visual Function Questionnaire.

Methods:

The case–control study comprised 26 patients with unilateral CRAO and a control group consisting of 26 control subjects, matched for age and sex. Vision-related quality of life was measured using the 39-item National Eye Institute Visual Function Questionnaire.

Results:

After Bonferroni correction, the median 39-item National Eye Institute Visual Function Questionnaire composite score was significantly lower in patients with CRAO than in those in the control group (Pcorr < 0.001). Patients with CRAO showed significantly lower median scores in 9 of 12 subscales: general vision (Pcorr < 0.001), peripheral vision (Pcorr < 0.001), difficulties with near-vision activities (Pcorr < 0.001), difficulties with distance-vision activities (Pcorr < 0.001), role difficulties as a result of vision problems (Pcorr < 0.001), dependency on others because of vision problems (Pcorr < 0.001), limitations in social functioning because of vision problems (Pcorr < 0.001), mental health symptoms because of vision problems (Pcorr < 0.001), and general health (Pcorr = 0.008).

Conclusion:

Our data suggest that vision-related quality of life is reduced in patients with CRAO.

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