PMID: 4099186

Issn Print: 0041-1337

Publication Date: 1970/11/01


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SOLUBILIZATION OF FETAL HL-A ANTIGENS: A Preliminary Report

M A Pellegrino; A Pellegrino; B D Kahan

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Abstract

SUMMARY

Water-soluble substances bearing HL-A antigenic determinants were extracted from the spleen, lung, liver, and kidney of 3-, 4-, and 5½ -month fetuses. These substances inhibited alloantisera in a pattern consistent with the phenotype of the antigen donor. There were significant differentials in the HL-A antigens which were solubilized from various tissues. Fetal kidney was the best source for the solubilization of HL-A antigens by sonic energy.

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