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The number of children participating in sports has risen steadily over the past few decades. As a result, the incidence of pediatric overuse injuries is rapidly increasing. Currently, primary care physicians are at the frontline in treating these injuries. It is important for these clinicians to be familiar with these types of injuries and their treatment options.This article reviews overuse injuries on the basis of location. It discusses the most recent literature describing their presentations, their treatment options, and suggested criteria for return to play.In summary, because the number of these injuries is on the rise, it is important for the physician to be aware of the clinical manifestations of overuse injuries, to prescribe current recommended treatments, and to educate patients in proper athletic conditioning.