Severe Bleeding Symptoms in Refractory Idiopathic Thrombocytopenic Purpura: A Case Successfully Treated With Melatonin

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The prognosis of patients with idiopathic thrombocytopenic purpura refractory to corticosteroids and splenectomy (refractory ITP) is poor; these patients present high morbidity from disease and its treatment and have a mortality rate of approximately 16%. A patient is reported with severe bleeding symptoms related to refractory ITP successfully treated with melatonin.

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