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Little has changed in how corneal surgery, particularly full-thickness penetrating keratoplasty, has been performed since the introduction of the operating microscope and microsurgery more than 40 years ago. The introduction of IntraLase Enabled Keratoplasty represents the first true advancement in corneal surgery in that time. There are numerous studies that have documented the high degree of complications seen in procedures such as penetrating keratoplasty. The advent of IntraLase Enabled Keratoplasty affords an opportunity to improve the safety and effectiveness of such procedures.Complications and visual outcomes remain an ongoing concern when it comes to managing patients following corneal surgery. The intensive postoperative follow up represents a significant undertaking for clinicians, staff and patients. Initial studies indicate that the use of the femtosecond laser in corneal surgery can simplify surgery, improve wound healing and lower levels of induced astigmatism.This review will examine the uses of the femtosecond laser in corneal surgery, as well as early results that have been reported.