The objective of this study is to determine the accuracy of the UEBE visomat handy device for blood pressure measurement in the wrist of patients tested according to the requirements of the International Protocol of the European Society of Hypertension (ESH). Device evaluation was done in 33 patients whose age and blood pressure were within the intervals required by the ESH protocol. Their mean±standard deviation age was 53.8±16.5 years (range 30–86 years), systolic blood pressure (SBP) was 143.5±20.2 mmHg (range 110–180 mmHg), diastolic blood pressure (DBP) was 87.4±12.9 mmHg (range 68–110 mmHg), arm circumference was 29.0±3.7 cm (range 21–38 cm), and wrist circumference was 17.3±1.5 cm (range 14.0–21.0 cm). During the measurements, which were taken in a sitting position, the patient's wrist was kept extended at the heart level putting a support under the forearm. In total, 45 measurements were available for analysis in the first phase of the validation process, and 99 measurements in the second phase. The visomat handy device passed all three phases of the ESH protocol for SBP and DBP. Mean blood pressure differences for the visomat handy monitor (device−observer) were −2.0±8.1 mmHg for SBP and −0.9±4.1 mmHg for DBP. These data show that the UEBE visomat handy wrist monitor met the requirements for validation by the International Protocol and can be recommended for clinical use in the adult population.