Laparoendoscopic single site surgery offers excellent cosmetic results and may be associated with decreased postoperative pain, reduced need for analgesia, and thus accelerated recovery. Preliminary experience with single-incision laparoscopic partial resection of the stomach for gastrointestinal stromal tumor (GIST) is reported. A single curved intraumbilical 25-mm incision was made with pulling out the umbilicus, and a 12-mm and two 5-mm ports were inserted. The submucosal gastric tumor located in the anterior wall of the stomach was resected with 2 endoscopic staplers under the retraction of 2-mm mini-loop retractor. The procedure was completed successfully without any perioperative complications, and there was no need to extend the skin incision. The operative time was 64 minutes. The final pathologic diagnosis was benign GIST. Postoperative follow-up did not reveal any umbilical wound complication. Laparoendoscopic single site partial resection of the stomach for GIST is feasible and a promising alternative method for scarless abdominal surgery.