DOI: 10.1097/01.pcc.0000448734.84859.22

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Issn Print: 1529-7535

Publication Date: 2014/05/01


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ABSTRACT 5: COMPLIANCE OF “SEPSIS_CARE_BUNDLE” ACCORDING THE SURVIVING SEPSIS CAMPAIGN GUIDELINES IN PEDIATRIC SEPTIC PATIENTS ADMITTED TO HOSPITALS IN LATIN AMERICA

D. Souza; H.H. Shieh; E.R. Barreira; E.J. Troster; L. Latin

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Author Information: PICU, University Hospital, Sao Paulo, Brazil

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Background and aims: The Surviving Sepsis Campaign (SSC) group has introduced the ‘sepsis care bundle’ into clinical practice with the goal of reducing mortality. Despite recent updating guidelines of SSC, data on the pediatric sepsis care bundle are scarce.
Aims: To report a ‘post hoc’ analysis of the rate of compliance of severe sepsis care bundle in pediatrics hospitals in Latin America.
Methods: A prospective study that evaluated children admitted to 21 PICUs in five countries (June-September/2011). The study was approved by the Committee of Ethics on Research, and informed consent was obtained. Patients with complete data in sepsis care bundle were included.
Results: Among the 1,090 patients of this study, the prevalence of severe sepsis was 25.9%, and 263 patients (95% of severe sepsis group) were included. The observed compliance to interventions: 98.8% fluid/colloid resuscitation, 60.8% serum lactate measured, 85.9% blood culture prior antibiotic administration, 44.5% broad-spectrum antibiotics until 1 hour for ICU admissions, 42.6 % achieve central venous oxygen saturation, 74.5% achieve central venous pressure, 88.6% glucose control maintained, and 30% of invasive arterial pressure monitoring.
Conclusions: Our study shows that the compliance of pediatric sepsis care bundle varied according to the intervention. Efforts and future studies to improve hospital mortality from severe sepsis could focus on increasing compliance with these evidence based interventions.

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