Postoperative Changes in Visual Evoked Potentials and Cognitive Function Tests Following Sevoflurane Anesthesia

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G. IOHOM, I COLLINS, D. MURPHY, I. AWAD, G. O’CONNOR, N. MCCARTHY AND G. SHORTEN
Department of Anesthesia and Intensive Care Medicine, Department of Clinical Neurophysiology and Department of Ophthalmology, Cork University Hospital and National University of Ireland, Cork, Republic of Ireland
Br. J. Anaesth., 87: 855–859, 2001
The hypothesis was tested that minor disturbances of the visual pathway persist after general anesthesia, even when clinical discharge criteria are met. Visual evoked potentials (VEPs) were measured in 13 ASA I or II patients who did not receive any preanesthetic medication and who underwent sevoflurane anesthesia. Visual evoked potentials were recorded on four occasions: before anesthesia and at 30, 60, and 90 min after emergence from anesthesia. Patients completed visual analog scales (VAS) for sedation and anxiety, a Trieger Dot Test (TDT), and a Digit Symbol Substitution Test (DSST) immediately before each VEP recording. The results were compared with the Student’s t-test. P < 0.05 was considered significant. Visual evoked potential latency was prolonged and amplitude diminished at 30, 60, and 90 min after emergence from anesthesia, when VAS scores for sedation and anxiety, TDT, and DSST had returned to preanesthetic levels.
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