DOI: 10.1097/DER.0000000000000113
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PMID: 25984695
Issn Print: 1710-3568
Publication Date: 2015/05/01
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Excerpt
Vitamin K is a group of 6 molecules derived from 2-methyl-1,4-naphthoquinone. Vitamin K1 (phylloquinone or phytomenadione) is an anticoagulant; its oxidized isoform is used in cosmetics as a lightening against hyperpigmentation of the skin1,2 and to prevent and to treat Epidermal Growth Factor Receptor inhibitors-related papulo-pustular eruption.3 Vitamin K2 (menaquinones) is synthesized by symbiotic bacteria in human gut flora. Vitamin K3 (menadione) is a synthetic organic fat-soluble molecule; its water-soluble form (menadione sodium bisulphite) is widely used as food supplement and as a veterinary antihemorrhagic drug. Vitamin K4 is used to treat neonatal hemorrhagic diseases and as an antifungal additive in animal feed, along with vitamin K5 and vitamin K6.
