Chronic Granulomatous Disease Presenting with Osteomyelitis: Favorable Response to Treatment with Interferon-γ

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A 3-year-old boy with chronic granulomatous disease presented with abscesses related to underlying osteomyelitis. Treatment with appropriate antibiotics resulted in resistance of the organisms. Treatment with interferon-γ was encouraging in that it caused the osteomyelitis to heal and prevented its relapse when used as long-term prophylaxis.

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