DOI: 10.1097/01.IDT.0000290220.14706.91

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Issn Print: 1936-9255

Publication Date: 2007/10/01


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Folate for Depression: Fabulous Facilitator or Fantastic Flop?

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Online quiz instructions: To take the quiz online, go to http://cme.LWWnewsletters.com, and enter your username and password. Your username will be the letters LWW (case sensitive) followed by the 12-digit account number on your mailing label. You may also find your account number on the paper answer form mailed with your issue. Your password will be 1234; this password may not be changed. Follow the instructions on the site. You may print your official certificate immediately. Please note: Lippincott CME Institute, Inc., will not mail certificates to online participants. Lippincott Continuing Medical Education Institute, Inc., is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. Lippincott Continuing Medical Education Institute, Inc., designates this educational activity for a maximum of 1 AMA PRA Category 1 Credit™. Physicians should only claim credit commensurate with the extent of their participation in the activity.
To earn CME credit, you must read the CME article(s) and complete the quiz and evaluation assessment survey on the enclosed form, answering at least 80% of the quiz questions correctly. Select the best answer and use a blue or black pen to completely fill in the corresponding box on the enclosed answer form. Please indicate any name and address changes directly on the answer form. If your name and address do not appear on the answer form, please print that information in the blank space at the top left of the page. Make a photocopy of the completed answer form for your own files and send the original answer form to Lippincott Williams & Wilkins, Office of Continuing Education Department, P.O. Box 1543, Hagerstown, MD 21741-9914 by September 30, 2008. For more information, call (800) 787-8981. The CME credits are included in the subscription price.
1. Genetic polymorphisms of 5,10-methylenetetrahydrofolate reductase are associated with impaired formation of:
A. Dihydrofolate
B. 5-methyltetrahydrofolate
C. Pteroylglutamic acid
D. Homocysteine
2. Which one of the following is the biologically active product of folate metabolism?
A. 5,10-methylenetetrahydrofolate
B. Tetrahydrofolate
C. [6S]-5-methyltetrahydrofolate
D. S-adenosyl-L-methionine
3. L-methylfolate is FDA-approved for the adjunctive treatment of major depressive disorder.
A. True
B. False
4. Folic acid fortification of grain products in the United States was made mandatory to reduce the risk of:
A. Neural tube defects
B. Atherosclerotic cardiovascular disease
C. Prostatic hypertrophy
D. Carcinoma of the breast
5. Which one of the following has been the main concern regarding the use of long-term folic acid supplementation?
A. Increased cardiovascular mortality
B. Progressive memory impairment
C. Masking manifestations of B12 deficiency
D.
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