DOI: 10.1097/01.BONEJ.0000434368.37926.70
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Issn Print: 1938-8659
Publication Date: 2013/09/01
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Excerpt
Yun Shen, MD, and colleagues in the Department of Orthopaedic Surgery at Xinhua Hospital in Shangri, China, found that significant differences in the microstructure of trabecular bone “convincingly” support the hypothesis.
According to Shen et al., although the relationship between OP and OA remains controversial, observation shows that both diseases rarely occur in the same patient. Further, the relationship between the two diseases may vary due to the location of bone mineral density (BMD) measurements, the type of OA (localized or generalized), and the stage of OA. They add that with an improved understanding of OP, the role of trabecular bone microstructure is widely acknowledged. “It is believed that 60% of the mechanical properties of bone depend on bone density, and the remaining [properties] may be associated with a number of factors related to bone quality,” they write.
Shen et al. note that the primary objective of the study was to explain the relationship between OA and OP on the basis of the difference in trabecular bone microstructure between these two diseases. Secondary objectives were to determine the significance of Euler number and its relationship with other structural parameters and the role of MRI in revealing the microstructure of trabecular bone.
