Relationship of optic materials with anterior and posterior capsule opacification as well as capculorhexis contraction of lenses

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Abstract

BACKGROUND:

Capsule opacification is a common complication following implantation of intraocular lenses for a long period. Scholars are looking for an ideal intraocular lens so as to reduce the incidence of capsule opacification.

OBJECTIVE:

To study the effects of three intraocular optic materials with sharp optic edge on anterior and posterior capsule opacification as well as capsulorrhexis contraction.

DESIGN, TIME AND SETTING:

A randomized controlled study was performed at the Department of Ophthalmology, Affiliated Hospital of Chengde Medical College from May 2005 to December 2006.

PARTICIPANTS:

A total of 135 patients (148 eyes) with age-related cataract, including 73 males (80 eyes) and 62 females (68 eyes) and aging 52-81 years with the mean age of (71.44 ±6.83) years, were collected in this study.

METHODS:

All patients were performed with phacoemulsification combining with implantation of foldable intraocular lenses which were characterized by sharp optic edges. Thereafter, they were randomly divided into three groups: lyophobic material group (n=43, 49 eyes), who were implanted with lyophobic acrylic acid intraocular lens; hydrophilic material group (n=42, 46 eyes), who were implanted with hydrophilic acrylic acid intraocular lens; lyophobic/hydrophilic material group (n=50, 53 eyes), who were implanted with lyophobic/hydrophilic acrylic acid intraocular lens.

MAIN OUTCOME MEASURES:

Anterior and posterior capsule opacification as well as capculorhexis contraction were quantitatively evaluated 1 year postoperatively.

RESULTS:

At one year postoperatively, incidences of posterior capsule opacification were 8.3% in the lyophobic material group, 26.7% in the hydrophilic material group, and 15.3% in the lyophobic/hydrophilic material group, respectively, and there was significant difference (P < 0.05); however, there were no significant differences in anterior capsule opacification and capculorhexis contraction among the three groups (P > 0.05).

CONCLUSION:

The optic intraocular lens of sharp optic edge does not have any effects on anterior capsule opacification or capsulorrhexis contraction, but has effects on formation of posterior capsule opacification; in particular, lyophobic acrylic acid can reduce the incidence to posterior capsule opacification.

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