System evaluation of curative effects of intraocular lens implantation for treating diabetic cataract

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Abstract

OBJECTIVE:

Controlled studies concerning intraocular lens implantation for treating diabetic cataract were analyzed using meta-analysis. Postoperative visual acuity and complications were assessed.

METHODS:

Controlled studies addressing intraocular lens implantation for treating diabetic cataract were collected from China National Knowledge Infrastructure (CNKI) from 1998 to 2008, Chinese Biological Medicine and Vip Database. Results were analyzed by meta-analysis. Experimental group contained diabetic cataract patients. Control group included non-diabetic cataract patients. Curative effects and difference evaluation index were expressed as odds ratio, weighed mean difference and 95% confidence interval (95%CI). Statistical analysis was analyzed using PEMS3.1 FOR WINDOWS software.

RESULTS:

A total of 6 randomized controlled literatures were collected. Meta-analysis results demonstrated that: ①Ratio of patients whose corrected vision ≥ 0.5 was lower in the diabetes group compared with the control group (P=0.004 8). Six literatures showed that OR value was 0.655 5 and 95%CI was (0.488 9, 0.879 0), which was in the left side of vertical line (P < 0.05). ②Occurrence rate of complications was greater in the diabetes group compared with the control group (P < 0.01). Six literatures showed that OR value was 4.570 and 95%CI was (2.729 0, 7.252 0), which was in the right side of the vertical line (P < 0.01).

CONCLUSION:

Corrected vision was lower, and the occurrence rate of complications was greater in the diabetes group compared with the control group following phacoemulsification and intraocular lens implantation.

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