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Abstract

BACKGROUND:

Using artificial bone materials as bone graft substitutes to repair bone defects is one of the important research subjects in medical and biomaterial fields.

OBJECTIVE:

To summarize the recent application status of bone repair materials in the treatment of fracture and bone defect.

METHODS:

An online search of VIP database was performed for articles related to the application of bone repair materials in the treatment of fractures and bone defects published between January 1998 and October 2009, with the key words of “fracture”, “bone repair”, “prosthetic replacement” and “material”. Articles with a high level of correlation were included. Repetitive studies were excluded. The collected articles were analyzed. The references of each article were checked. A total of 26 articles were retained in the end.

RESULTS AND CONCLUSION:

The recent researches on bone repair materials are focused on nano-hydroxyapatite/polyamides-66, demineralized bone matrix, calcium sulfate particles and nanometer crystal hydroxyapatite/collagen composite. Nano tissue-engineered bone material is a new kind of material using nanotechnology. It is based on nano structured units or with the magnitude of 1 to 100 nm. Experiments on animals confirm that the developed nano-hydroxyapatite/collagen have better biocompatibility and bioactivity than regular hydroxyapatite. It promotes and accelerates bone wound healing.

RESULTS AND CONCLUSION:

Zhai X. Value of bone repair materials in the treatment of fractures and bone defects. Zhongguo Zuzhi Gongcheng Yanjiu yu Linchuang Kangfu. 2011;15(51):9655-9658. [http://www.crter.cnhttp://en.zglckf.com]

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