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The present studies of the anti-wear are focused on the improvement and choice of the joint surface. The surface of metal-on-metal is the most important direction of reform and investigation.


To explore the feasibility and the utilization information after 12 months of metal-on-metal prosthesis of total knee arthroplasty (TKA) in rabbits and evaluate the biomechanical characteristics of the prosthesis.


The prostheses were designed personally, surfaces of femoral and tibial prostheses were reformed by stainless steel-mesh, friction surfaces were used to match metal-on-metal. Ten adult New Zealand rabbits underwent TKA and non-replacement of the patella were divided randomly into two groups (5 in each group). The experimental prosthesis was fixed biologically and the control group was used with bone cement.


At 12 months after replacement, a great amount of bone reconstructions were found in the experimental group. The difference of function of the knee joint between the two groups was not significant. Roentgenograms proved that two groups were fixed well and no dislocation and no loosening. The maximal shear strength of prosthesis bone interface in the experimental group was higher than that in the control group (P < 0.05).There were new bone formation of the thick stereo mesh surface of the prosthesis in the experimental group and no new bone formation of the surface of the cementless prosthesis in the control group under fluorescence microscopy. The metal-on-metal prosthesis of TKA is suitable to be fixed biologically for the rabbits, no matter whether use bone cement or not. The fixation strength of prosthesis by two layer stainless steel-mesh is better than that of the bone cement prosthesis at 12 months after operation.


Liu JH, Yu SM, Hu JY, Xu DL. Feasibility of metal-on-metal prostheses for total knee arthroplasty in rabbits.Zhongguo Zuzhi Gongcheng Yanjiu yu Linchuang Kangfu. 2011;15(52): 9691-9695. [http://www.crter.cn]

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