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As the high blood clotting of the elderly patients, the complications may occur more easily after cemented hip replacement, such as deep venous embolism, disseminated intravascular coagulation, pulmonary embolism and cerebral embolism.


To explore the changes of four blood clots index, such as the prothrombin time (PT), activated partial thromboplastin time (APTT), thrombin time (TT) and fibrinogen (FIB) after cemented hip replacement in elderly patients.


The PT, APTT, TT and FIB of 40 elderly patients with artificial hip replacement was detected at 10 minutes before implantation and 30 minutes, 1, 2, 3 hours after implantation, respectively.


Compared with 10 minutes before implantation, the PT of 30 minutes after implantation was significantly decreased (P < 0.05), and the FIB was increased obviously (P < 0.05), and restored to the normal state at 3 hours after implantation (P > 0.05). The changes of APTT and TT before and after implantation were not significant (P > 0.05). The results showed that there were high blood clots in a short time after bone cement implantation, and disappeared at 3 hours after implantation. Three hours after bone cement implantation was the best time to detect the blood clots.


Liu HB, Yang LC, Meng QB. Changes of blood clotting in elderly patients prior to and after cemented hip replacement.Zhongguo Zuzhi Gongcheng Yanjiu yu Linchuang Kangfu. 2011;15(52): 9756-9759. [http://www.crter.cn]

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