SymbolSalvage liver transplantation as a rescue operation for recurrent hepatocellular carcinoma after partial hepatectomy

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Abstract

BACKGROUND:

As donor organs shortage are serious at present, salvage liver transplantation strategy offers a new way to solve the problem.

OBJECTIVE:

To contrast the efficacies of salvage liver transplantation for postoperative tumor recurrence and primary liver transplantation in hepatocellular carcinoma patients who meet Milan criteria.

METHODS:

A total of 53 hepatocellular carcinoma patients with tumor met Milan criteria who underwent liver transplantation in the Department of Hepatobiliary Surgery of Fuzhou General Hospital from July 2001 to August 2009 were included. Among them, 12 cases met the Milan criteria of postoperative tumor recurrence and received salvage liver transplantation. While 41 patients received primary liver transplantations.

RESULTS AND CONCLUSION:

The operation time, anhepatic phase, the volume of blood loss, suspension red blood cell transfusion during operation, ICU time, total hospitalization time, the total cost of hospitalization in salvage liver transplantation group were significantly larger than that in the primary liver transplantation group (P > 0.05). There was no significant difference in fresh frozen plasma transfusion between the two groups (P < 0.05). There was no significant difference in the overall survival rates between the two groups throughout the follow-up period of 39 months (P > 0.05). It demonstrates that liver resection prior to liver transplantation can be integrated with the treatment strategy for hepatocellular carcinoma patients with tumor meets Milan criteria.

RESULTS AND CONCLUSION:

Xia YJ, Pan F, Lü LZ, Cai QC, Yang F, Jiang Y. Salvage liver transplantation as a rescue operation for recurrent hepatocellular carcinoma after partial hepatectomy. Zhongguo Zuzhi Gongcheng Yanjiu yu Linchuang Kangfu. 2011;15(53): 9889-9892. [http://www.crter.cnhttp://en.zglckf.com]

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