SymbolApplication of artificial dural repair materials in neurosurgery

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BACKGROUND:Artificial dural repair materials are widespreadly used because they have numerous features, such as abundant resources, no antigenicity, do not adhere to the inferior brain tissues, are easy to prepare, clip and suture.OBJECTIVE:To summarize the application progress of artificial dural repair materials in neurosurgery.METHODS:A computer-based online search of China National Knowledge Infrastructure, China Journal Full-text Database, China Doctoral Dissertations Full-text Database, Chinese Master's Theses Full-text Database, China Biology Medicine Database and VIP database was performed for articles related to brain injury repair using artificial dura mater, with the key words of “artificial dura mater”, “dura mater repair” and “brain injury”. A total of 146 articles were collected after primary search, 23 of them were retained in the end according to the inclusion criteria.RESULTS AND CONCLUSION:In the past, self tissue repair has been widely used to repair the dura mater defects; but it has certain limitations in the clinical application because of its own disadvantages, such as limited sources, the possibility to cause a new wound and increasing pain to patients. Therefore, self-tissue, such as muscular fasciae, can be used to repair small defects; while for the large dural defects, artificial dura substitute materials are often required. Using alternative materials to repair dura defects is essential for the maintenance of anatomical integrity and brain protection in neurosurgery. Artificial dura mater has superiority over the autologous dura mater in the practical application of dura mater defects repair. However, due to the existence of histocompatibility and other inevitable shortcomings, dural repair materials still need to be further studied.Tao XH. Application of artificial dural repair materials in neurosurgery. Zhongguo Zuzhi Gongcheng Yanjiu. 2012;16(12): 2217-2220. [http://www.crter.cn]

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