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Abstract

BACKGROUND:

With the advanced progress of medicine and tissue engineering technology, a variety of biomaterials have emerged, and how to choose the suitable membrane materials becomes the key for artificial lung technology development.

OBJECTIVE:

To evaluate the performance of various ventilator membrane biomaterials, and to find the appropriate materials.

METHODS:

An electronic retrieval of Wanfang database (http://www.wanfangdata.com.cn/) from January 1991 to December 2011 was performed for articles about the biological materials applied in ventilator membrane research, using the key words for “film, artificial lung, biological material” in Chinese. Duplicated documents, reviews and Meta analysis were excluded. A total of 20 articles were involved in the evaluation, including 11 Chinese literatures and nine English literatures.

RESULTS AND CONCLUSION:

The structure of artificial lung membrane had been developed from drum, plate folding to microporous hollow fiber membrane which is widely used now. The hollow fiber materials are mainly polymers with high performance of fiber formation, such as polypropylene and poly(ether sulfone). Membrane-type artificial lung can improve gas exchange and biocompatibility. With the development of new technologies and materials, the advance of basic research and the accumulation of clinical experience, artificial lung is bound to initiate new insight in the treatment of severe respiratory disorders.

RESULTS AND CONCLUSION:

Wang S. Selection and biocompatibility of ventilator membrane materials. Zhongguo Zuzhi Gongcheng Yanjiu. 2012;16(12): 2221-2224. [http://www.crter.cnhttp://en.zglckf.com]

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