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Abstract

BACKGROUND:

Current used materials for clinical reconstruction of cruciate ligaments of knee joint include autograft, allograft and artificial materials. Autograft and allograft are main selection for reconstruction of cruciate ligaments. However, there are some limitations.

OBJECTIVE:

To discuss optimal selection of artificial materials for ligament injury of the knee joint.

METHODS:

A computer-based online search of Wanfang database (http://www.wanfangdata.com.cn/) and PubMed database (http://www.ncbi.nlm.nih.gov/PubMed) was performed for articles related to bioengineering design and clinical application of artificial ligaments published between January 1988 and December 2010 with key words “artificial ligament, tissue engineering, reconstruction”. After excluding repetitive and Meta analysis articles, 20 were included for further analysis.

RESULTS AND CONCLUSION:

Although there are progresses in artificial ligament, some issues are needed to resolve. Seed cell selection, histocompatibility and mechanics of stent materials, cell and stent material interface biocompatibility are focuses in studies regarding artificial ligaments. With further investigation, tissue engineered artificial ligaments can be clinically used early.

RESULTS AND CONCLUSION:

Kang JM, Zuo J. Artificial ligament materials and ligament injury of the knee joint. Zhongguo Zuzhi Gongcheng Yanjiu. 2012;16(12): 2241-2244. [http://www.crter.cnhttp://en.zglckf.com]

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