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Ideal prosthetic materials are important to the function and prognosis of artificial knee joint.


To evaluate the properties, application and biocompatibility of biomaterials for artificial knee joint, and to search ideal knee substitutes.


A computer-based search of Wanfang database (1999-01/2009-12) was performed for articles regarding biomaterials used in artificial knee joint using the keywords of “tissue engineering, artificial knee joint, biomaterials” in Chinese. Repetitive studies, review and Meta analysis were excluded, and finally 17 articles were included in result analysis.


Traditional metal and bone cement materials are still widely used in the knee prosthesis. With the development of medicine and tissue engineering technology, various synthetic biomaterials have appeared. Recently, bio-ceramic and polymer composites with good biocompatibility have been found, but easy to wear is a disadvantage for the bio-ceramic and polymer composites. To modify the above-mentioned materials and seek the ideal knee prosthesis materials is one of the hot spots in the current biomedical engineering research. Although traditional metal, bone cement, bio-ceramic and polymer composites are widely used in clinical artificial knee, the ideal knee prosthesis materials need further studies because of their inevitable shortcomings.


Qin XD, Li CJ, Fu Q. Commonly used prosthetic materials for artificial knee joint and their biocompatibility. Zhongguo Zuzhi Gongcheng Yanjiu. 2012;16(12): 2257-2260. [http://www.crter.cn]

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