Symbol: Fibrovascularization of different types of hydroxyapatite orbital implants

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Abstract

BACKGROUND:

Hydroxyapatite orbital implant is the best intraocular implant which has broad application prospects.

OBJECTIVE:

To evaluate the degree of fibrovascularization of different types of hydroxyapatite orbital.

METHODS:

The fibrovascularization degree of natural hydroxyapatite orbital implants with different pore sizes and synthetic hydroxyapatite orbital implants was evaluated with radionuclide, MRI imaging and histopathological examination, and the effect of basic fibroblast growth factor collagen on the fibrovascularization of hydroxyapatite orbital implants was analyzed.

RESULTS AND CONCLUSION:

Radionuclide, MRI imaging and histopathological examination could clearly display the process and degree of fibrovascularization of hydroxyapatite orbital, and the examination results showed that the vascularization could be completed generally in 6-8 weeks, and the speed of fibrovascularization of natural hydroxyapatite orbital was faster than that of synthetic hydroxyapatite orbital, and there was positive correlation between the pore size and the speed of fibrovascularization. Basic fibroblast growth factor could promote the vascularization of hydroxyapatite orbital.

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