Combined treatment ofHUOXUEBUSHENDecoction and bone impaction grafting for nontraumatic osteonecrosis of the femoral head

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Abstract

BACKGROUND:

The treatment of osteoporosis of the femoral head relies on the reconstruction and improvement of blood supply in the femoral head, maintenance of femoral head structure, restoration of mechanical environment and blood supply in femoral head. Traditional Chinese medicine treatment is very advantageous. Bone impaction grafting through a femoral neck window at high location can restore the mechanical environment in femoral head.

OBJECTIVE:

To investigate clinical efficacy of combined treatment of HUOXUEBUSHEN decoction and bone impaction grafting through a femoral neck window at high location for non-traumatic osteoporosis of the femoral head.

METHODS:

This study is a prospective controlled trial. The patients with non-traumatic osteoporosis of the femoral head were divided into two groups: treatment group (n=52, 60 hips) and control group (n=51, 60 hips). The treatment group was given a combined treatment of HUOXUEBUSHEN decoction and bone impaction grafting through a femoral neck window (the decoction was prepared in People's Hospital of Linyi, China). The control group underwent simple bone impaction grafting through a femoral neck window. All the involved patients were followed up for 12 months, Harris hip score and the excellent-good rate at the last follow-up were used to evaluate clinical efficacy.

RESULTS AND CONCLUSION:

The Harris score, pain degree, and joint range of motion scores in the treatment group were higher than that in control group (P < 0.01), but joint deformities and functional scores showed no significant differences between two groups (P > 0.05). The excellent-good rate in the treatment group was significantly higher than that in control group (88%, 75%; χ2=4.91, P < 0.05). The combined treatment of HUOXUEBUSHEN decoction and bone impaction grafting through a femoral neck window at high location is effective in the treatment of non-traumatic osteonecrosis of the femoral head, and is better than simple bone impaction grafting at alleviating pain and improving joint range of motion.

Subject headings:

drugs, Chinese herbal; femur head necrosis; bone transplantation; pain; range of motion, articular

Subject headings:

Wei BF, Sun BY. Combined treatment of HUOXUEBUSHEN Decoction and bone impaction grafting for nontraumatic osteonecrosis of the femoral head. Zhongguo Zuzhi Gongcheng Yanjiu. 2014;18(29):4706-4711.

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